The Chromatin Digest

Category: essays-and-discussions

  • Should we rethink the histone code?

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    by

    Isabella
    in

    Histone modifications and their conventional notation. From Fig. 1 of Turner, 2005. “Dream of complications / On and on / That’s how my observation tends” – Interpol, “Complications” off their 2018 album, Marauder I was reading a paper earlier and the tiniest thing jumped out at me: the histone modification H3K27me3 written inversely as me3K27H3.…

  • How it all started, and where we are now

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    by

    Isabella
    in

    On the evolution of epigenetics, both as a field and as a term (and my first post!) A diagram of a developing human embryo from a 1916 textbook (image is in the public domain). The meaning of words changes over time. “Awful”, for instance, used to mean “impressive”. Now it means quite the opposite. “Epigenetics”…