In Conversation With… Yolanda Markaki
Yolanda Markaki is a group leader and microscopist based at the University of Leicester, UK. Her lab, set up in 2023, focuses on the mechanisms of X chromosome inactivation. She is also passionate about gender equality in science. Thank you for joining me! Can you please tell me a bit about what you are working…
In Conversation With… Jonathan Henninger
Jonathan Henninger runs a laboratory at Carnegie Mellon University, in Pittsburgh, PA, USA. His lab explores how RNA molecules regulate gene expression at multiple scales in health and disease. Can you tell me a little bit about your background and where you are now? Yeah, absolutely. I did my undergraduate degree in my hometown, at…
Old proteins, new tricks
In order to switch genes on and off, chromatin has to be opened and shut, enabling the DNA to become open to the whim of the rest of the nucleus for transcription. This is called chromatin remodelling, and it’s far from an easy task because our DNA is wrapped around huge protein complexes called nucleosomes.…